The Genomics and Metagenomics Research Program internship 2025

The Genomics and Metagenomics Research Program (GMRP) at CCHE 57357 Hospital is a cutting-edge research facility dedicated to advancing the fields of genomics, epigenomics, pharmacogenomics, and metagenomics through high-throughput, next-generation sequencing technologies and third-generation sequencing. As the first of its kind in Egypt, GMRP is equipped with state-of-the-art platforms for comprehensive genomic analyses, including whole genome sequencing, whole exome sequencing, transcript omics, microbiome profiling, and epigenomic mapping. These capabilities enable us to investigate the genetic and epigenetic underpinnings of complex diseases and the dynamics of microbial communities in clinical and environmental contexts. Our lab is dedicated to advancing the understanding of antimicrobial resistance, viral genomics, and cancer biology. Through these diverse research areas, we aim to address critical health challenges and contribute significantly to both basic and applied biomedical science.

The program will enhance participants’ ability to troubleshoot experiments and apply theoretical knowledge to real-world research.

Week 1 Objectives:

By the end of this week participants will be able to:

1. Comprehensive overview of Genomics, Metagenomics & Epigenomics:
   a. Describe the structure and role of DNA and RNA
   b. Clarifying how gene expression is regulated
   c. Clarifying the principles of sequencing technologies, and bioinformatics.
2. Hands-on Laboratory Skills:
   a. Demonstrate DNA/RNA extraction techniques
   b. Quantify and assess nucleic acid purity using NanoDrop™
   c. Operate the LabChip GX Touch Nucleic Acid Device
   d. Evaluate DNA size and quality based on output data

Week 2 Objectives:

By the end of this week participants will be able to:
1) Explain the principles of gene expression and real-time PCR
2) Apply real-time PCR techniques
3) Explain the theoretical principles of microarray technology
4) Apply microarray techniques

Week 3 Objectives:

By the end of this week, participants will be able to:
(Next-Generation Sequencing (NGS) Technologies):
– Identify the principles and workflows of Whole Exome Sequencing (WES) and Whole Genome Sequencing (WGS), including library preparation, quality checks, and sequencing
– Identify the principles and workflows of 16S Metagenomics and mRNA profiling, including library preparation, quality checks, and sequencing.

Week 4 Objectives:

By the end of this week participants will be able to:

1. Identify the principles of miRNA profiling (Theoretical introduction to principles, library prep, quality checks, and sequencing.)
2. Introduction to Bioinformatics:
   1. Acquire basic skills in handling sequencing data
   2. Define file formats
   3. Perform downstream analysis

2 days / week for 4 weeks
(Monday, Wednesday)

Both undergraduate and fresh graduate from medical, biotechnological, pharmaceutical, agriculture, and scientific tools.

In order to receive your certificate, you have to attend not less than 80%

• Hard copy for 300 Egyptian Pounds
• Soft copy for free